buprenorphine subdermal implant and pentobarbital both maximize sedation. Prevent or Use Alternate Drug. Limit use to sufferers for whom choice cure solutions are insufficientpentobarbital will minimize the extent or effect of ombitasvir/paritaprevir/ritonavir & dasabuvir (DSC) by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicat